Prognostic significance of KIF23 expression in gastric cancer
نویسندگان
چکیده
منابع مشابه
Prognostic Significance of p21 and p53 Expression in Gastric Cancer
BACKGROUND Cyclin-dependent kinase inhibitors (CDKI), including p21, p27 and p57 of the KIP family, are negative regulators of cell cycle progression and potentially act as tumor suppressors. The expression of p21 is induced by tumor suppressor gene p53. Mutations of p53 are common and found in various human cancers. Thus, the function of p21 as a tumor suppressor may be not retained after p53 ...
متن کاملAugmented expression levels of lncRNAs ecCEBPA and UCA1 in gastric cancer tissues and their clinical significance
Objective(s): As the second cause of cancer death, gastric cancer (GC) is one of the eminent dilemmas all over the world, therefore investigating the molecular mechanisms involved in this cancer is pivotal. Unrestricted proliferation is one of the characteristics of cancerous cells, which is due to deficiency in cell regulatory systems. Long non-coding RNAs (lncRNAs) have emerged as critical re...
متن کاملEvaluation of the Prognostic Value and TRIP13 gene Expression in Gastric Cancer
Introduction: Gastric cancer is a major public health issue worldwide. The factors that initiate cancer are not well understood, however aberrant expression of genes is associated with this cancer. TRIP13 plays pivotal roles in meiotic recombination, DNA repair, and cell cycle progression. An increasing body of evidence suggests that TRIP13 may possess functions other than meiosis and mitosis, ...
متن کاملSignificance of CD47 expression in gastric cancer
Integrin-associated protein (CD47) is ubiquitously expressed on the surface of cells and functions as an identifier of self. In blood cancer, tumor cells expressing CD47 evade phagocytosis by macrophages, leading to a poor patient prognosis. However, the status of CD47 expression in solid tumors, particularly in gastric cancer, is not well understood. The purpose of the present study was to exa...
متن کاملthe prognostic significance of her2-neu over expression in gastric carcinomas
background: h e r2/ n eu i so n e o ftheepi de rmalg r owth f actor r e c e pt o rsfami l i e s andsee m stohaveprognosticsignificanceofsomesolid t umors.theo b jecti v eof thisstu d yistoevaluatet h epossi b ilityofher2ex p ressioningastricca n cersand the p o s si b le r e lat i o n ship o fh e r2withtumo r ’scli n icopat h o l o gicpara m e te r sa n d a l s oits pr o gno s tic r o l e . m...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: World Journal of Gastrointestinal Oncology
سال: 2020
ISSN: 1948-5204
DOI: 10.4251/wjgo.v12.i10.1104